National Association for Pseudoxanthoma Elasticum (NAPE)
Pseudoxanthoma elasticum (PXE) An excellent resource for information on PXE or the ocular side effect of Angioid Streaks. Angioid streaks are broad, irregular, red to brown to gray lines which radiate from the area around the optic nerve head under the retinas of individuals with pseudoxanthoma elasticum (). These streaks or striations are typically bilateral and vary in width from 50 to 100 microns, barely detectable by ophthalmoscopy, to 3-4 times the average retinal vascular width, dramatically visible to the casual ophthalmic observer. Their borders are irregular, serrated, and occasionally ill-defined, particularly when they are smaller than the blood vessels in that region. Their number and extent are variable, as are their age of onset. Their course tends to be more sinuous and angular than normal retinal blood vessels. State support groups are listed.